PATHOGNOMONIC SIGNS OF DIFFERENT DISEASES

Pathognomonic sign is a particular sign of a disease whose presence intensifies that a disease is present without any hesitations. Here are the list of the most common diseases and their pathognomonic signs:

1. Addison’s Dse. - Bronze-like skin
2. Appendicitis-McBurney’s Point/ Rovsing Sign/Psoas Sign
3. Asthma-Wheezing Inspiration
4. Bulimia Nervosa - Chipmunk Face
5. Cataract- Blurry Vision / Hizzy Vision
6. Cholecystitis-Murphy’s Sign (pain RUQ)
7. Cholera -Rice Watery Stool
8. COPD -Barrel-Chested
9. Cushing Syndrome- Buffalo Hump
10. Dengue-Petechiae
11. Down Syndrome- Single Crease on Palm/Clubbing of Fingernails
12. Glucoma- Tunnel-like Vision
13. Hepatitis-Icteric Sclera (yellowish discoloration of sclera)
14. Hyperpituitarism - CAROTENEMIA (Discoloration of skin)/ XANTHAMIA
15. Hyperthyroidism - Exopthalmus
16. Kawasaki Dse.- Strawberry Tongue
17. Leprosy-Leoning Face (contracted face)
18. Liver Cirrhosis - Spider Angioma
19. Malaria -Stepladder Fever
20. Measles-Koplick’s Spot
21. Meningitis-Burdzinski Sign (Pain on nape)/Karnig Sign (pain on leg/ knee area)
22. MI-Levine's sign
23. Myasthemia Gravis (MG) - Ptosis (inability to open upper eyelids)
24. Pancreatitis - Cullen Sign (Bluish discoloration preumbilical area)
25. Parkinson’s Dse. - Pill Rolling Tremors
26. Pernicious Anemia - Beefy Red Tongue (Schilling’s Test)
27. Pneumonia - Greenish Rusty Sputum
28. PTB-Low grade fever in afternoon
29. Pyloric Stenosis - Olive-Shaped Mass
30. SLE-Butterfly Rashes
31. Tetany- Chvostek Sign)/Trosseau’s Sign
32. Thrombophlebitis - Homan’s Sign
33. Typhoid - Rose Spot